Blar i Bergen Open Research Archive på forfatter "Grøndal, Sturla Magnus"
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AXL is a driver of stemness in normal mammary gland and breast cancer
Engelsen, Agnete; Wnuk-Lipinska, Katarzyna; Bougnaud, Sébastien; Vatter, Fanny A. Pelissier; Tiron, Crina Elena; Villadsen, René; Miyano, Masaru; Lotsberg, Maria Lie; Madeleine, Noëlly; Panahandeh, Pouda; Dhakal, Sushil; Tan, Tuan Zea; Peters, Stacey D'Mello; Grøndal, Sturla Magnus; Aziz, Sura Mohammed; Nord, Silje; Herfindal, Lars; Stampfer, Martha R.; Sørlie, Therese; Brekken, Rolf A; Straume, Oddbjørn; Halberg, Nils; Gausdal, Gro; Thiery, Jean Paul; Akslen, Lars A.; Petersen, Ole W.; LaBarge, Mark A.; Lorens, James (Journal article; Peer reviewed, 2020)The receptor tyrosine kinase AXL is associated with epithelial plasticity in several solid tumors including breast cancer and AXL-targeting agents are currently in clinical trials. We hypothesized that AXL is a driver of ... -
C/EBPB-dependent adaptation to palmitic acid promotes tumor formation in hormone receptor negative breast cancer
Liu, Xiaozheng; Rulina, Anastasiia; Choi, Man Hung; Pedersen, Line; Lepland, Johanna; Takle, Sina Thorsen; Madeleine, Noëlly; Peters, Stacey D'mello; Wogsland, Cara Ellen; Grøndal, Sturla Magnus; Lorens, James Bradley; Goodarzi, Hani; Lønning, Per Eystein; Knappskog, Stian; Molven, Anders; Halberg, Nils Henrik (Journal article; Peer reviewed, 2022)Epidemiological studies have established a positive association between obesity and the incidence of postmenopausal breast cancer. Moreover, it is known that obesity promotes stem cell-like properties of breast cancer ... -
High-dimensional immunotyping of tumors grown in obese and non-obese mice
Wogsland, Cara Ellen; Lien, Hilde Eide; Pedersen, Line; Hanjra, Pahul; Grøndal, Sturla Magnus; Brekken, Rolf A; Lorens, James Bradley; Halberg, Nils Henrik (Journal article; Peer reviewed, 2021)Obesity is a disease characterized by chronic low-grade systemic inflammation and has been causally linked to the development of 13 cancer types. Several studies have been undertaken to determine whether tumors evolving ... -
Mass cytometry analysis of the tumour-immune landscape: The role of Axl receptor kinase
Grøndal, Sturla Magnus (Master thesis, 2018-12-08)Cancer is one of the leading causes of death in Norway (2016) and worldwide. Despite the advent of new immunotherapies, malignant cancer demonstrates an intrinsic plasticity and is able to evade, adapt and suppress the ...